Low Voltage TEM for Cell Biology

In cell biology, the high contrast imaging provided by a LVEM is a major advantage. Electron microscopy in general allows for the study of the activities, functions, properties and organization of cells. This provides a deep understanding of organization and function within cells.

Electron microscopy approaches complement light microscopy by providing greater detail. Electron microscopy is the only technique with sufficient resolution to localize proteins to small membrane subdomains within the cell. Researchers can better understand the location and organization of organelles, actin filaments in the cytoskeleton, and molecular complexes such as nuclear pores.

Although there are instances where staining is desirable for diagnostic purposes, the necessity to stain samples in order to generate adequate detailed contrast cannot be viewed as advantageous. The LVEM microscopes still allows for staining as an option, yet high contrast result are acquired from samples in their inherent, natural state. The LVEM25 has the added benefit of being able to work with conventionally prepared thin sectioned materials. This provides images without the side effects often encountered such as staining artifacts or the sample crashing out by chemical reaction with heavy metals.

Electron microscopy traditionally is one of the most demanding techniques to learn. However, the simplicity of the LVEM5 and LVEM25 combined with the elimination of the staining step makes it accessible to many more researchers.

The versatile LVEM5 electron microscope operates with four distinct imaging modes; TEM, SEM, STEM and ED. This provides for comprehensive imaging and finer study. The more powerful LVEM25 is built upon the same platform as the LVEM5 and offers the same benefits, together with higher beam energy.

Whether it’s in the fields of pathology or other life sciences, researchers and medical professionals are assured of top notch imaging with LVEM microscopes

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